SS12 : Late-Breaking Clinical Trials

Updated:Aug 27,2014
Science News From Scientific Sessions 2012 
 

Late-Breaking Clinical Trials

Sunday, Nov. 4, 2012Monday, Nov 5, 2012Tuesday, Nov. 6, 2012

LBCT.01: Practice Implications for CAD and VTE

LBCT.03: Treatments for Prevention of Cardiovascular Events: A Population Perspective

LBCT.05: Cell-Based Therapies for Myocardial Regeneration

LBCT.02: Health Economics and Quality of Life in Contemporary Trials

LBCT.04: Novel Treatments for Managing Lipid Disorders

LBCT.06: Management of LV Dysfunction: Devices and Drugs


Sunday, Nov. 4, 2012

LBCT.01: Practice Implications for CAD and VTE


Tim Brighton
Prince of Wales Hospital
Sydney, Australia
 
Aspirin for The Prevention of Recurrent Venous Thromboembolism After a First Unprovoked Event: Results of the ASPIRE Randomized Controlled Trial

Gilles Montalescot

Pitié-Salpêtrière University Hospital
Paris, France
A Randomized Trial of Bedside Platelet Function Monitoring to Adjust Antiplatelet Therapy Versus Standard of Care in Patients Undergoing Drug Eluting Stent Implantation: The ARCTIC Study

Paul A Gurbel

Sinai Hospital Center for Thrombosis Research
Baltimore, Md. 
First Large-Scale Platelet Function Evaluation in an Acute Coronary Syndromes Trial - The TRILOGY ACS Platelet Function Sub-study
 
Gervasio A Lamas
Mount Sinai Medical Center
Miami, Fla.
Results of the Trial to Assess Chelation Therapy

Valentin Fuster

Mount Sinai School of Medicine
New York, N.Y. 
Main Results of the Future REvascularization Evaluation in Patients with Diabetes Mellitus: Optimal management of Multivessel disease (FREEDOM) Trial
 
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LBCT.02: Health Economics and Quality of Life in Contemporary Trials

Thomas R Porter
University of Nebraska Medical Center
Omaha, NE
Prospective Evaluation of Outcomes With Stress Perfusion Imaging Versus Stress Wall Motion Imaging During Dobutamine or Exercise Echocardiography


 
Eric L. Eisenstein
Duke Clinical Research Institute
Durham, NC
Economic Outcomes of Percutaneous Coronary Intervention Performed at Sites With and Without On-Site Cardiac Surgery
 
Daniel B. Mark
Duke University Medical Center
Durham, NC
Quality of Life Outcomes in the Trial to Assess Chelation Therapy (TACT)
 

Elizabeth A Magnuson
Saint Luke's Mid America Heart Institute
Kansas City, MO
Cost-Effectiveness of PCI with Drug Eluting Stents versus Bypass Surgery for Patients with Diabetes and Multi-vessel Coronary Artery Disease: Results from the FREEDOM Trial
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Monday, Nov. 5, 2012

LBCT.03: Treatments for Prevention of Cardiovascular Events: A Population Perspective


Alejandro Macchia

Consorzio Mario Negri Sud
Santa Maria Imb, Italy
Omega-3 fatty Acids for the Prevention of Recurrent Symptomatic Atrial Fibrillation: Results of a double-blind randomized clinical trial (FORWARD)
Presentation Slides (PDF)  |  Summary Slide (PDF)  |  Presentation Audio (mp3)  |  Discussant Audio (mp3) 

Roberto Marchioli

Consorzio Mario Negri Sud
Santa Maria Imbaro, Italy 
Fish Oil for the Prevention of Post-Operative Atrial Fibrillation - The Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation (OPERA) Trial
Presentation Slides (PDF)  |  Summary Slide (PDF)  |  Presentation Audio (mp3)  |  Discussant Audio (mp3)   

Howard D Sesso
Brigham and Womens Hospital
Boston, MA
A Randomized Trial of a Multivitamin in the Prevention of Cardiovascular Disease in Men: The Physicians’ Health Study II
Presentation Slides (PDF) | Summary Slide (PDF)  
Simon A Thom
Imperial Coll London
London, United Kingdom 
Use of a Multidrug Pill In Reducing cardiovascular Events (UMPIRE)
Summary Slide (PDF)  
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LBCT.04: Novel Treatments for Managing Lipid Disorders


Jay Horton
Dallas, TX
Overview of PCSK9 Inhibition in the Treatment of Hyperlipidemia
Presentation Slides (PDF)

 Frederick Raal
Universotu of Witwatersrand Johannisburg
South Africa
Reduction of LDL-C with PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder (RUTHERFORD): Results from a Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial
Presentation Slides (PDF) | Summary Slide (PDF) 

 Evan Stein
Metabolic and Atherosclerosis Research Center Cincinnati, OH
Goal Achievement after Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects (GAUSS): Interim Results from a Randomized, Double-blind, Placebo-controlled Study
Summary Slide (PDF) 

 Barry Gumbiner
Pfizer, Inc.
San Diego, CA
Effects of 12 Weeks of Treatment with RN316 (PF-04950615), a Humanized IgG2Δa Monoclonal Antibody Binding Proprotein Convertase Subtilisin Kexin Type 9, in Hypercholesterolemic Subjects on High and Maximal Dose Statins
Summary Slide (PDF) 

Gregory G Schwartz

VA Medical Center and University of Colorado
Denver, CO 
Effects of the Cholesteryl Ester Transfer Protein Inhibitor Dalcetrapib in Patients with Recent Acute Coronary Syndrome
Presentation Slides (PDF) | Summary Slide (PDF) 
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Tuesday, Nov. 6, 2012

LBCT.05: Cell-Based Therapies for Myocardial Regeneration


Stefanie Dimmeler
Frankfurt, Germany
Overview of the Field of Cell-based Therapies for Myocardial Regeneration
Presentation Slides (PDF) 

Daniel Sürder

Fondazione Cardiocentro Ticino
Lugano, Switzerland
Results of the Swiss Multicenter Intracoronary Stem Cells Study in Acute Myocardial Infarction (Swiss Ami) Trial 
Presentation Slides (PDF) | Summary Slide (PDF)

Naofumi Takehara

Kyoto Prefectual University of Medicine
Kyoto, Japan 
The ALCADIA (Autologous Human Cardiac-derived Stem Cell To Treat Ischemic Cardiomyopathy) Trial
Summary Slide (PDF)

Jay H Traverse

Minneapolis Heart Institute at Abbott Northwestern Hospital
Minneapolis, MN

The Effect of Timing of Stem Cell Delivery Following Acute Myocardial Infarction: The NHLBI and CCTRN TIME Trial
Summary Slide (PDF)


Joshua M Hare

University of Miami School of Medicine
Miami, FL 
Randomized Comparison of Allogeneic vs Autologous Mesenchymal Stem Cells in Patients with Ischemic Cardiomyopathy (Posiedon)
Presentation Slides (PDF) | Summary Slide (PDF)

Roberto Bolli

University of Louisville
Louisville, KY 
Effect of Cardiac Stem Cells in Patients with Ischemic Cardiomyopathy: Interim Results of the SCIPIO Trial Up to 2 Years After Therapy
Summary Slide (PDF)
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LBCT.06: Management of LV Dysfunction: Devices and Drugs


Arthur J. Moss

Univ of Rochester Medical Ctr, Rochester, NY
MADIT Randomized Trial to Reduce Inappropriate Therapy (MADIT-RIT)
Summary Slide (PDF)

Anne B. Curtis

University at Buffalo
Buffalo, NY 
Biventricular versus Right Ventricular Pacing in Patients with Left Ventricular Dysfunction and Atrioventricular Block (BLOCK HF Study)
Presentation Slides (PDF) | Summary Slide (PDF)

Esteban Lopez-de-Sa

Hosp Univrio La Paz Madrid, Spain 
Pilot Trial of Two Levels of Hypothermia in Comatose Survivors from Out-of-Hospital Cardiac Arrest
Summary Slide (PDF)  
 
John R Teerlink
San Francisco VAMC UCSF
San Francisco, CA
The RELAXin in Acute Heart Failure (RELAX-AHF) Trial
Summary Slide (PDF)

 Bradley A Bart
Hennepin County Medical Center
Minneapolis, MN
Cardiorenal Rescue Study in Acute Decompensated Heart Failure: Results of CARRESS-HF, for the Heart Failure Clinical Research Network
Summary Slide (PDF)
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