Science News: ESC Congress 2014

Updated:Sep 2,2014


SCIENCE NEWS - covering the science presented daily at ESC Congress 2014 with video highlights, summary slides for late-breaking clinical trials presented in Hot Line sessions, and links to AHA science and resources related to the Hot Line science each day.

Sunday
HOT LINE I —CARDIOVASCULAR DISEASE: NOVEL THERAPIES

PARADIGM-HF: Results of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial

NECTAR-HF: A randomized controlled trial of vagal stimulation for the treatment of systolic heart failure: NEural Cardiac TherApy foR Heart Failure

CONFIRM-HF: Effect of ferric carboxymaltose on functional capacity in patients with heart failure and iron deficiency

MORE-CRT: Cardiac resynchronization therapy with a novel quadripolar lead decreases complications at six months: preliminary results

POPE 2: Colchicine for Post- operative Pericardial Effusion: The post-operative pericardial effusion Study. A multicenter, double-blind, randomized trial

COPPS 2: COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation


HOT LINE II — CORONARY ARTERY DISEASE AND LIPIDS

SOLID-TIMI 52: The Stabilization Of pLaques usIng Darapladib-Thrombolysis in Myocardial Infarction 52 trial: Primary Results

SIGNIFY: Ivabradine in patients with stable coronary artery disease without clinical heart failure

ODYSSEY COMBO II: Efficacy and safety of alirocumab in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia on maximally tolerated daily statin

ODYSSEY FH I & FH II: Efficacy and safety of alirocumab in patients with heterozygous familial hypercholesterolaemia not adequately controlled with current lipid-lowering therapy

ODYSSEY LONG TERM: Long-term safety, tolerability and efficacy of alirocumab versus placebo in high cardiovascular risk patients: first results from 2,341 patients.

LISTEN: The differences of the effects on lipid-lowering actions and glucose metabolisms between rosuvastatin and atorvastatin in Japanese diabetic patients with hyperlipidemia.


Monday
HOT LINE III — HEART FAILURE: DEVICES AND INTERVENTIONS

BIOSCIENCE: Randomized comparison of a novel, ultrathin strut biodegradable polymer sirolimus-eluting stent with a durable polymer everolimus-eluting stent for percutaneous coronary revascularization

ANTHEM-HF: Autonomic regulation therapy for the improvement of left ventricular function and heart failure symptoms

BIOPACE: Biventricular pacing for atrIo-ventricular BlOck to Prevent cArdiaC dEsynchronization

SEPTAL CRT: Comparison of right ventricular septal pacing and right ventricular pacing in patients receiving a CRT-D

STAR AF 2: Optimal method and outcomes of catheter ablation of persistent atrial fibrillation: Results of the Prospective, Randomized Trial

EuroEco: (European Health Economic Trial on Home Monitoring in ICD Patients)- a provider perspective on follow-up costs and net financial impact of remote monitoring in six European countries


HOT LINE IV — MYOCARDIAL INFARCTION

CvLPRIT: Complete versus Lesion only PRimary -PCI Trial: Treat the infarct related artery only or all lesions

ATLANTIC: In-ambulance versus in-cath lab administration of ticagrelor in STEMI patients transferred for primary PCI: the randomized, double-blind study

FAMOUS-NSTEMI: The British Heart Foundation Fractional Flow Reserve versus Angiography in Guiding Management to Optimise Outcomes in Non-ST-Segment Elevation Myocardial Infarction

NOMI: Nitric oxide for inhalation to reduce reperfusion injury in acute st-elevation myocardial infarction

MITOCARE: Effect of intravenous TRO40303 as an adjunct to primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: Results of the Study


Tuesday
HOT LINE V — CORONARY ARTERY DISEASE AND ATRIAL FIBRILLATION

STICS: Perioperative statin treatment in cardiac surgery for the prevention of atrial fibrillation and perioperative myocardial damage: the Statin Therapy In Cardiac Surgery Trial

X-VERT: A comparison of oral rivaroxaban once daily with dose-adjusted Vitamin K Antagonists in patients with nonvalvular atrial fibrillation undergoing elective cardioversion

AMIO-CAT: Recurrence of arrhythmia following short-term oral AMIOdarone after CATheter ablation for atrial fibrillation: A double-blind, randomized, placebo-controlled study

IBIS4: Effect of high-intensity statin therapy on atherosclerosis in patients with ST-elevation myocardial infarction: Results of the prospective, longitudinal intravascular ultrasound follow-up study

IMPI: A Trial of Adjunctive Prednisolone in Tuberculous Pericarditis





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