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The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction

  • “Omics” studies promise to deepen our understanding of cardiovascular diseases and stroke and improve our ability to diagnose, predict, and prognosticate diseases in individual patients—a key goal of precision medicine.
  • We now have the ability to address disease on levels that were inaccessible to us during the last century: the genome, transcriptome, epigenome, proteome, metabolome, cells, tissues, and organs.
  • A critical step towards the widespread use of the expressed genome in the clinic is funding of large-scale efforts to validate, replicate, and integrate the information streams arising from various -omics studies.

Read the full article in Circulation: Cardiovascular Genetics