Postmenopausal CV Health: Recent Studies from the Women's Health Initiative

Updated:Feb 19,2013

Postmenopausal  Cardiovascular Health:  Recent Studies from the Women’s Health Initiative

Lessons Learned
JE Rossouw, JE Manson, AM Kaunitz, GL Anderson.
Source: Obstetrics & Gynecology
Abstract only

Health risks and benefits from calcium and vitamin D supplementation: WHI clinical trial and cohort study
RL Prentice, MB Pettinger, RD Jackson et al.
Source: Osteoporosis International
Open Access


Calcium supplementation did not increase risk of heart disease.

Statin use and risk of diabetes mellitus in postmenopausal women in the WHI
AL Culver, IS Ockene, R Balasubramanian
Source: Arch Intern Med. 2012;172(2):144-152


 New onset diabetes is associated with statins.

Between Annual Visit-to-Visit Blood Pressure Variability and Stroke in Postmenopausal Women Novelty and Significance Data
D Shimbo, JD Newman, AK Aragaki, MJ et al.
Source: Mo Med. 2011 Nov-Dec;108(6):431-8.


 Increased visit-to-visit variability of blood pressure is associated with stroke.

Effects of Postmenopausal Hormone Therapy on Incident Atrial Fibrillation
MV Perez, PJ Wang, JC Larson et al.
Source: Circ Arrhythm Electrophysiol. 2012;5:1108-1116.


AF modestlyl elevated in hysterectomized women randomized to estrogen.

Racial and Ethnic Differences in Incident Hospitalized Heart Failure in Postmenopausal Women
CB Eaton, AM Abdulbaki, KL  Margolis et al.
Source: Circulation. 2012;126:688-696.
 Asian/Pacific Islander and Hispanic women had lower incidence of HF and black women had higher rates of HFcompared with white women.

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