Strategically Focused Research Network Awardees

Updated:Apr 29,2015



The AHA is currently funding two Strategically Focused Research Networks:

  • Northwestern University (Ill.), Vanderbilt University (Tenn.), Icahn School of Medicine at Mount Sinai (N.Y.), and the University of Texas, Southwestern, form the Strategically Focused Prevention Research Network.
  • The University of Iowa, the Medical College of Wisconsin, Cincinnati Children's Hospital, and the University of Alabama, Birmingham form the Strategically Focused Hypertension Research Network.

 

Strategically Focused Hypertension Research Network
Award Activation: April 1, 2015

Cincinnati Children's Hospital

Center Director
Elaine Urbina, MD, MS, FAHA

Basic
Project PI: Richard Becker, MD, FAHA
Influence of Regulatory Genome on Target Organ Damage in Youth with Primary Hypertension

Clinical
Project PI: Joseph Flynn, MD, MS
Hemodynamic and Metabolic Predictors of Target Organ Damage in Youth with Primary Hypertension

Population
Project PI: Elaine Urbina, MD, MS, FAHA
Threshold for Development of Blood Pressure-Related Target Organ Damage in Youth

Medical College of Wisconsin

Center Director
Mingyu Liang, MB, PhD

Basic
Project PI: David L. Mattson, PhD, FAHA
Epigenetic Modification of Immune Mechanisms in Salt-Sensitive Hypertension and Renal Damage

Clinical
Project PI: Srividya Kidambi, MD
Epigenomics of Hypertension in Monozygotic Twins and Effect of Salt Intake

Population
Project PI: Theodore A. Kotchen, MD, FAHA
Epigenomic Modifications in Hypertension and Hypertension-Related Cardiovascular Diseases

University of Alabama at Birmingham

Center Director
Paul Muntner, PhD, MHS

Basic
Project PI: Jennifer Pollock, PhD, FAHA
Novel Mechanisms of Salt-sensitivity and Diurnal Blood Pressure Rhythm

Cinical
Project PI: David Calhoun, MD, FAHA
Mechanisms of Nocturnal Hypertension and Non-dipping Blood Pressure

Population
Project PI: Paul Muntner, PhD, MHS
Racial Differences and US population estimates of Nocturnal Hypertension and Non-dipping

University of Iowa

Center Director
Curt D. Sigmund, PhD, FAHA

Basic
Project PI: Justin L. Grobe, PhD, FAHA
Molecular Mechanisms of Vasopressin-Induced Preeclampsia

Clinical
Project PI: Gary L. Pierce, PhD, MS
Early Vascular Dysfunction and Elevated Copeptin in Human Preeclampsia

Population
Project PI: Mark K. Santillan, MD
Predicting Preeclampsia via Copeptin: Underrepresented Minorities & Synergy with Other Biomarkers



Strategically Focused Prevention Research Network
Award Activation: July 1, 2014

Icahn School of Medicine at Mount Sinai Strategically Focused Prevention Research Center

Center Director
Valentin Fuster, MD, PhD, FAHA

Basic
Project PI: Eric Schadt, PhD
Applying Cross-generation Genetic and Genomic Information to Improve Cardiovascular Disease Prevention

Clinical
Project PI: Zahi Fayad, PhD, FAHA
Two Intensive Life Style Intervention Programs in Related Caregivers of Preschool Children

Population
Project PI: Valentin Fuster, MD, PhD, FAHA
Children Heart Research Study Program

Northwestern University Strategically Focused Prevention Research Center

Center Director
Philip Greenland, MD, FAHA

Basic
Project PI: Lifang Hou, MD, MS, PhD
Epigenetics of Cardiovascular Health Metrics 

Clinical

Project PI: Bonnie Spring, PhD, FAHA
mHealth Intervention to Preserve and Promote Ideal Cardiovascular Health

Population
Project PI: Norrina Allen, PhD
Trajectories in Cardiovascular Health (CVH) Metrics and Score From Childhood through Middle-Age

University of Texas Southwestern Strategically Focused Prevention Research Center

Center Director
Joseph Hill, MD, PhD, FAHA

Basic
Project PI: Joseph Hill, MD, PhD, FAHA
Molecular mechanisms in the transition from cardiomyocyte hypertrophy to HFpEF

Clinical
Project PI: Benjamin Levine, MD
Novel HFpEF Prevention Strategies In High Risk Individuals: High Intensity Exercise Training Plus Omega-3 Fatty Acids

Population
Project PI: Jarrett Berry, MD
Association Between Physical Activity and Modifiable Intermediate Heart Failure Phenotypes

Vanderbilt University Strategically Focused Prevention Research Center

Center Director
David Harrison, MD, FAHA

Basic
Project PI: David Harrison, MD, FAHA
Effect of Salt on Innate and Adaptive Immune Cells in Hypertension

Clinical
Project PI: Jens Titze, MD
Lowering Tissue Na+ Stores to Reduce Blood Pressure, Systemic Inflammation, and Metabolic Derangement in Aging Humans

Population
Project PI: Thomas Jue-Fuu Wang, MD, FAHA
Prevention of Hypertension and its Complications in a Medically-Underserved Population

 

 


Strategically Focused Research Network News

Heart disease survivor donates $5 million to fund research center for heart disease in women
The American Heart Association Blog
May 19, 2015

UAB selected to take part in $15M study on high blood pressure

Birmingham Business Journal
April 17, 2015

UAB selected as site of AHA's new SFRN on hypertension
UAB News
April 17, 2015

AHA-funded network boosts blood pressure research
The American Heart Association Blog
April 10, 2015

Research funding gap widens at AHA
The American Heart Association Blog
March 30, 2015

Preventing Heart Disease in New York City Children and Their Caregivers
Mt. Sinai Hospital
July 15, 2014

Feinberg Selected for New American Heart Association Network
Northwestern University Feinberg School of Medicine
July 11, 2014

AHA grant creates coalition to prevent heart disease, stroke
Vanderbilt University
July 10, 2014

AHA funds new research network aimed at preventing heart disease, stroke
The American Heart Association
June 27, 2014

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