AHA Cardiovascular Genome Phenome Study (CVGPS)

Please note, the CVGPS Grand Challenge Award application process and timeline have changed.  See the Letter of Intent Requirements for more information.  The full application will be due December 2, 2014.

American Heart Association Cardiovascular Genome Phenome Study (CVGPS) Funding Announcement

The Cardiovascular Genome Phenome Study (CVGPS) is a collaborative effort, spearheaded by the American Heart Association (AHA), to accelerate the future of cardiovascular medicine. CVGPS combines the power of long-term population studies with the precision of molecular analysis to unravel key distinctions between and within subgroups of patients. The discoveries it generates will point the way toward better-targeted, safer, and more effective treatments, based on a deeper understanding of patients’ characteristics, including e.g. risk profiles and therapeutic needs.

The CVGPS is a collaboration among AHA, Boston University (BU) and the University of Mississippi Medical Center (UMMC), the academic coordinating center homes, respectively, of the Framingham Heart Study (FHS) and the Jackson Heart Study (JHS). The Jackson Heart Study also involves Jackson State University (JSU) and Tougaloo College (TC) as partner institutions.

Through the rich diversity of constituent participant/patient populations, CVGPS research will bring inter-individual and patient-to-patient differences into ever sharper focus for common diseases such as atherosclerosis and hypertension.

To accomplish the promise of the CVGPS, AHA is offering two funding opportunities to investigators:

CVGPS Pathway Grants

  • Funded at $250,000/year for 2 years for a total of $500,000
  • Application deadline for first round of Pathway Grants has passed.  Awardees will be announced in November 2014.
  • Pathway Grants will be offered again in 2015.

CVGPS Grand Challenge Awards

For more information about the desired characteristics, requirements for the application, letter of application and peer review criteria view the full Request for Applications (PDF).

CVGPS Frequently Asked Questions    

View the Cardiovascular Genome Phenome Study Awardees