Bugher Foundation Awardees

Updated:Jul 21,2014

AHA_ASA_Together_2013Bugher_2013

American Stroke Association/Bugher Foundation Centers of Excellence in Stroke Collaborative Research for Regeneration, Resilience and Secondary Prevention
Award Activation: April 1, 2014



University of California, Los Angeles
S. Thomas Carmichael, MD, PhD, FAHA - Center Director   
Center Title: University of California, Los Angeles ASA/Bugher Foundation Center of Excellence in Stroke Collaborative Research
Award start date: 4/1/2014  Award End Date: 3/31/2018  Total Award Amount: $2,416,000

Bruce Dobkin, MD - Project 1 PI
Institution: University of California, Los Angeles
Project Title: Feedback from daily activity sensing to enhance exercise for secondary prevention and rehabilitation after stroke

S. Thomas Carmichael, MD, PhD, FAHA - Project 2 PI
Institution: University of California, Los Angeles
Project Title: Discovery of Molecular Mechanisms of White Matter Repair after Stroke

Latisha Ali, MD, FAHA - Project 3 PI
Institution: University of California, Los Angeles
Project Title: REMote PReconditioning Over Time to Empower Cerebral Tissue (REM-PROTECT)

University of Colorado, Denver
Richard Traystman, PhD - Center Director   
Center Title: University of Colorado Denver | Anschutz Medical Campus ASA/Bugher Foundation Center of Excellence in Stroke Collaborative Research
Award start date: 4/1/2014  Award End Date: 3/31/2018  Total Award Amount: $2,416,000

Timothy Bernard, MD - Project 1 PI
Institution: University of Colorado, Denver
Project Title: Childhood Stroke Neuropsychological and Quality of Life Outcomes: Exploring lesion-specific plasticity

Paco Herson, PhD - Project 2 PI
Institution: University of Colorado, Denver
Project Title: Neuronal Injury and Functional Recovery following Experimental Pediatric Arterial Ischemic Stroke

Wendy Macklin, PhD - Project 3 PI
Institution: University of Colorado, Denver
Project Title: Glial responses in pediatric stroke

University of Miami
Ralph Sacco, MD, MS, FAHA, FAAN - Center Director   
Center Title: University of Miami ASA/Bugher Foundation Center of Excellence in Stroke Collaborative Research
Award start date: 4/1/2014  Award End Date: 3/31/2018  Total Award Amount: $2,416,000

Clinton Wright, MD - Project 1 PI
Institution: University of Miami
Project Title: The Effects of Exercise, Cognitive Training, or Both on Cognition and Quality of Life Post-stroke

Miguel Perez-Pinzon, PhD, FAHA - Project 2 PI
Institution: University of Miami
Project Title: Enriched Environment, Exercise and Neurotherapeutics to Enhance Functional Recovery Following Stroke
 

American Stroke Association/Bugher Foundation Centers for Stroke Prevention Research
Award Activation:  July 1, 2007


Duke University
Larry Goldstein, MD - Center Director
    
Center Title: Bugher Foundation Center for Stroke Prevention Research
Award start date: 7/1/2007  Award End Date: 6/30/2011  Total Award Amount: $2,660,000

Larry Goldstein, MD - Project 1 PI
Institution: Duke University
Project Title: Small Vessel-Type Intracranial Disease Risk: Whole Genome Association Studies

Cheryl Bushnell, MD - Project 2 PI
Institution: Wake Forest University
Project Title: Biomarkers and Nitric Oxide Synthase Genotypes in African Americans with Intracranial Small Vessel-Type Disease

Massachusetts General Hospital
Karen Furie, MPH, MD - Center Director

Center Title: Harvard ASA-Bugher Center for Stroke Prevention & Genetic Research
Award start date: 7/1/2007  Award End Date:  6/30/2011  Total Award Amount: $2,101,280

Jonathan Rosand, MD, MSc - Project 1 PI
Institution: Massachusetts General Hospital
Project Title: Genetic Determinants and Outcomes of White Matter Hyperintensity

Dong Kim, MD - Project 2 PI
Institution: University of Texas, Houston
Project Title: Identification of Coding Variants Associated with Cerebral Aneurysm Pathogenesis

University of California, Davis
Frank Sharp, MD - Center Director
Center Title: ASA-Bugher Foundation Center for Stroke Prevention Research: Genomics and Genetics of TIA's and Stroke in Humans
Award start date: 7/1/2007  Award End Date: 6/30/2011  Total Award Amount: $2,660,000

Piero Verro, MD - Project 1 PI
Institution: University of California, Davis
Project Title: Genomics and Genetics of TIAs and Stroke in Humans. Project #1: Genomic Prediction of Causes of Ischemic Stroke

S. Claiborne Johnston, MD, Ph.D.  
Institution: University of California, San Francisco
Project Title: Genomics and Genetics of TIAs and Stroke in Humans. Project #2:Genomic Diagnosis and Assessment of Causes of TIAs
 

AHA-ASA Bugher Foundation Award for the Investigation of Stroke
Award Activation:  July 1, 2005


Massachusetts General Hospital
Eng Lo, PhD
Project Title: Matrix metalloproteinases in stroke recovery
Award start date: 7/1/2005  Award End Date: 6/30/2009  Total Award Amount: $400,000

Oregon Health & Science University, Portland
Stephen Back, MD, PhD  
Project Title: Role of Extracellular Matrix in Hypoxic-ischemic Perinatal White Matter Injury
Award start date: 7/1/2005  Award End Date: 6/30/2009  Total Award Amount: $400,000

Oregon Health &Science University, Portland
Patricia Hurn, PhD    
Project Title: Sex Specific Ischemic Cell Signaling
Award start date: 7/1/2005  Award End Date: 12/30/2009  Total Award Amount: $400,000

University of Cincinnati
Stephen Page, PhD    
Project Title: Electrical stimulation dosing and neural mechanisms of recovery in subacute stroke
Award start date: 7/1/2005  Award End Date: 6/30/2009  Total Award Amount: $397,464

University of Iowa, Iowa City
Frank Faraci, PhD    
Project Title: Role of Oxidative Stress in Cerebral Circulation During Aging
Award start date: 7/1/2005  Award End Date: 6/30/2009  Total Award Amount: $400,000

University of Kentucky
William Maragos, MD, PhD
Project Title: Targeted mitochondrial uncoupling in focal cerebral ischemia
Award start date: 7/1/2005  Award End Date: 6/30/2009  Total Award Amount: $400,000

Wayne State University
Kenneth Maises, MD   
Project Title: Mobilizing the Wnt Gene Against Oxidative Stress During Stroke
Award start date: 7/1/2005  Award End Date: 6/30/2009  Total Award Amount: $400,000

Weill Medical College of Cornell University
Susan Vannucci, PhD  
Project Title: Substrate Intervention and Ischemic Neuroprotection in Developing Brain
Award start date: 7/1/2005  Award End Date: 6/30/2009  Total Award Amount: $400,000
 

Bugher Foundation Awards for the Investigation of Stroke
Award Activation:  Jan. 1, 2002


Baylor College of Medicine, Houston
Robert Bryan, PhD
Project Title: Endothelium-Derived Hyperpolarizing Factor in Cerebral Vessels Involves Arachidonic Acid
Award start date: 1/1/2002  Award End Date: 12/31/2005  Total Award Amount: $400,000

Henry Ford Health Systems
Robert Knight, DSc
Project Title: Evaluation of Blood Barrier Disruption in Acute Cerebral Ischemia
Award start date: 1/1/2002  Award End Date: 12/31/2005  Total Award Amount: $398,660

Johns Hopkins University
Rafael Tamargo, MD
Project Title: The Inflammatory Hypothesis of Cerebral Vasospasm: Leukocytes as Mediators and Therapeutic Targets
Award start date: 1/1/2002  Award End Date: 12/31/2005  Total Award Amount: $400,000

Nemours Children's Clinic, Wilmington
N. Carolyn Schanen, MD, PhD
Project Title: Determining the Role of Notch3 in Vascular Smooth Muscle Cell Homeostasis
Award start date: 1/1/2002  Award End Date: 12/31/2005  Total Award Amount: $400,000

Stanford University School of Medicine
Pak Chan, PhD
Project Title: Oxidative Stress and Metalloproteinases in Blood- Brain Barrier Injury in the Ischemic Brain
Award start date: 1/1/2002  Award End Date: 12/31/2005  Total Award Amount: $400,000

University of Chicago Hospitals
Robert Macdonald, MD, PhD
Project Title: Role of Potassium Channels in Cerebral Vasospasm
Award start date: 1/1/2002  Award End Date: 12/31/2005  Total Award Amount: $400,000

Wake Forest University Baptist Medical Center
David Busija, PhD
Project Title: Effects of Insulin Resistance on Cerebrovascular Responsiveness and Stroke in Rats
Award start date: 1/1/2002  Award End Date: 12/31/2005  Total Award Amount: $400,000
 

Bugher Foundation Awards for the Investigation of Stroke
Award Activation:  Jan. 1, 2001


Barrow Neurological Institute, Phoenix
Eric Johnson, PhD

Project Title: Genetics of Neurovascular Disease
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

Brigham and Women's Hospital
James Liao, MD

Project Title: Rho-Induced Cytoskeletal Regulation of Endothelial Nitric Oxide Synthase
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

Mayo Clinic, Rochster
Irene Meissner, MD
Project Title: Metabolic and Inflammatory Mechanisms in Atherosclerosis
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

Medical University of South Carolina
Ling Wei, MD
Project Title: Effects of bFGF and VEGF on Angiogenesis and Long-term Functional Recovery after Ministroke in the Mouse
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

Medical University of South Carolina
Shan Yu, MD, PhD
Project Title: Potassium Channel Modulation in Apoptosis and Effects of Potassium Channel Blockers on Ischemic Cell Death
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

University of California, Los Angeles
Chelsea Kidwell, MD
Project Title: Characterizing the Ischemic Penumbra and Response to Intra-arterial Thrombolytic Therapy in Humans Using Diffusion/Per…
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

University of Chicago Hospitals
Richard Kraig, PhD, MD

Project Title: Cyclooxygenase, Interleukin-1 & Spreading Depression-Induced Modulation of Excitoxic Brain Injury
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

University of Iowa, Iowa City
Steven Lentz, MD, PhD
Project Title: Methionine Metabolism, Cerebral Vascular Dysfunction, and Thrombosis
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

University of Kansas Medical Center
Randolph Nudo, PhD
Project Title: Neural Bases for Effects of Amphetamine on Motor Recovery After Stroke
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000

University of Pennsylvania
Vladimir Muzykantov, MD, PhD
Project Title: Thromboprophylaxis for Cerebral Microembolism
Award start date: 1/1/2001  Award End Date: 12/31/2004  Total Award Amount: $400,000
 

Bugher Foundation Awards for the Investigation of Stroke
Award Activation:  Jan. 1, 2000


Allegheny-Singer Research Institute
Stephen Jones, PhD  
Project Title: Cerebral Blood Flow Regulation in Hypotension and Ischemia
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $400,000

Duke University
Douglas Marchuk, PhD
Project Title: Molecular Genetic Analysis of Cerebral Cavernous Malformations
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $400,000

Indiana University, Bloomington
Zao Xu, M.D., PhD
Project Title: Mechanisms of Neuronal Injury in Hippocampus After Cerebral Ischemia
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $388,188

Louisiana State University, Shreveport
John (He) Zhang, MD, PhD
  
Project Title: Signal Transduction in Cerebral Vasospasm
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $400,000

Mayo Medical School, Rochester
Zvonimir Katusic, MD, PhD
  
Project Title: Expression and Function of Recombinant Nitric Oxide Synthase Gene in Human Cerebral Arteries
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $389,385

Stanford University School of Medicine
Rona Gifford, PhD, MD
Project Title: Brain Cell Vulnerability to Cerebral Ischemia and Acidosis-The Sodium Bicarbonate Cotransporter
Award start date: 7/1/2000  Award End Date: 6/30/2004  Total Award Amount: $400,000

University of Cincinnati
Frank Sharp, MD

Project Title: Role of Hypoxia Inducible Factor in Stroke
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $400,000

University of Maryland, Baltimore
J. Marc Simard, MD, PhD
Project Title: Regulation of Cerebrovascular Smooth Muscle Gap Junction Channels by Endothelium and Second Messengers
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $383,341

University of Pennsylvania
Mark Kahn, MD
Project Title: Molecular Identification and Characterization of the Signaling Receptor for Collagen on Human Platelets
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $400,000

Washington University School of Medicine
Colin Derdeyn, MD
Project Title: The Effect of HMG-CoA Reductase Inhibitors on CBF in Humans
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $399,422

Yale University
Pasko Rakic, MD, PhD
Project Title: The Role of Jun Kinase and Caspase in Neuronal Apoptosis Induced by Ischemia-Hypoxia
Award start date: 1/1/2000  Award End Date: 12/31/2003  Total Award Amount: $379,328

 


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