Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal
Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal Models
| - This study seeks to understand how CD4+T-cell subsets are related to the atherosclerosis process.
- In humans and in animal models the effector memory T cell subset (TEM) was associated with an increase in atherosclerosis as well as coronary artery disease.
- When these T cells block T-cell antigen dependent recognition in experimental models, protection against atherosclerosis has been demonstrated.
Read the full article in JAHA
Enrico Ammirati, Domenico Cianflone, Viviana Vecchio, Michela Banfi, Anna C. Vermi, Monica De Metrio, Liliana Grigore, Fabio Pellegatta, Angela Pirillo, Katia Garlaschelli, Angelo A. Manfredi, Alberico L. Catapano, Attilio Maseri, Alessio G. Palini, and Giuseppe D. Norata. J Am Heart Assoc. 2012;1:27-41, doi:10.1161/JAHA.111.000125.
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Supporting Materials - Editorial: Hyperlipidemia as an Instigator of Inflammation: Inaugurating New Approaches to Vascular Prevention by Paul M Ridker, MD, FAHA
- Top 10 Things To Know
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