2015 Distinguished Scientist - Samuel Z. Goldhaber, MD, FAHA
Samuel Z. Goldhaber, MD, Professor of Medicine at Harvard Medical School, is Section Head of Vascular Medicine in the Cardiovascular Medicine Division at Brigham and Women’s Hospital (BWH). He is Director of the BWH Thrombosis Research Group and serves as Principal Investigator of a broad range of randomized clinical trials and observational studies related to the prevention, treatment, and epidemiology of venous thromboembolism, stroke prevention in atrial fibrillation, and prevention of recurrent myocardial infarction.
Dr. Goldhaber showed through a series of clinical trials that right ventricular dilatation and hypokinesis predict an adverse prognosis in acute pulmonary embolism. Furthermore, these trials showed that systemic and catheter-based ultrasound-facilitated thrombolytic therapy more rapidly than heparin restored normal right ventricular function. He also conducted a randomized trial demonstrating that electronic medical alerts for high risk inpatients not receiving venous thromboembolism prophylaxis reduce the symptomatic DVT and pulmonary embolism rates by more than 40 percent.
Dr. Goldhaber serves as Chair of the Steering Committee of the National Heart, Lung, and Blood Institute (NHLBI)-sponsored ATTRACT Trial of DVT, which is testing pharmacomechanical low-dose thrombolysis against standard anticoagulation to prevent postthrombotic syndrome. He serves on the Steering Committees of the GARFIELD Atrial Fibrillation and GARFIELD-Venous Thromboembolism cohort studies and is National Coordinator of U.S. participating sites. For his work on prevention of venous thromboembolism, Dr. Goldhaber has received the Certificate of Appreciation from the Surgeon General of the United States.
Dr. Goldhaber directs a series of Harvard Medical School CME courses, including a 5-day update in clinical cardiology and a 2-day course on thrombosis and thromboembolism. He also tapes the “Clot Blog” for theheart.org on Medscape.
Dr. Goldhaber is President and Founding Director of the nonprofit organization, North American Thrombosis Forum. He serves as a Section Editor of Clinician Update and the Cardiology Patient Page for Circulation. He runs a busy outpatient practice of general cardiology, venous thromboembolism, and atrial fibrillation patients, and oversees the inpatient Cardiology Consult Service.